PROLYL 4 HYDROXYLASE
\pɹˈɒlɪl fˈɔː hˈa͡ɪdɹəksˌɪle͡ɪs], \pɹˈɒlɪl fˈɔː hˈaɪdɹəksˌɪleɪs], \p_ɹ_ˈɒ_l_ɪ_l f_ˈɔː h_ˈaɪ_d_ɹ_ə_k_s_ˌɪ_l_eɪ_s]\
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A mixed-function oxygenase that catalyzes the hydroxylation of a prolyl-glycyl-containing-peptide, usually in protocollagen, to a hydroxyprolylglycyl-containing-peptide. The enzyme utilizes molecular oxygen with a concomitant oxidative decarboxylation of 2-oxoglutarate to succinate. EC 1.14.11.2.
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