PREMATURITY RETINOPATHIES
\pɹɪmət͡ʃˈʊ͡əɹɪti ɹˌɛtɪnˈɒpəθɪz], \pɹɪmətʃˈʊəɹɪti ɹˌɛtɪnˈɒpəθɪz], \p_ɹ_ɪ_m_ə_tʃ_ˈʊə_ɹ_ɪ_t_i ɹ_ˌɛ_t_ɪ_n_ˈɒ_p_ə_θ_ɪ_z]\
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A bilateral retinopathy occurring in premature infants treated with excessively high concentrations of oxygen, characterized by vascular dilatation, proliferation, and tortuosity, edema, and retinal detachment, with ultimate conversion of the retina into a fibrous mass that can be seen as a dense retrolental membrane. Usually growth of the eye is arrested and may result in microophthalmia, and blindness may occur. (Dorland, 27th ed)
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Word of the day
Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.