PINCHGUT
\pˈɪnt͡ʃɡʌt], \pˈɪntʃɡʌt], \p_ˈɪ_n_tʃ_ɡ_ʌ_t]\
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.