PICROPODOPHYLLIN
\pˈɪkɹəpˌɒdəfˌɪlɪn], \pˈɪkɹəpˌɒdəfˌɪlɪn], \p_ˈɪ_k_ɹ_ə_p_ˌɒ_d_ə_f_ˌɪ_l_ɪ_n]\
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A decomposition product of podophyllotoxin.
By Smith Ely Jelliffe
Word of the day
Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.