PHOTOSENSITIVE CONTACT DERMATITIS
\fˌə͡ʊtə͡ʊsˈɛnsɪtˌɪv kˈɒntakt dˌɜːmɐtˈa͡ɪtɪs], \fˌəʊtəʊsˈɛnsɪtˌɪv kˈɒntakt dˌɜːmɐtˈaɪtɪs], \f_ˌəʊ_t_əʊ_s_ˈɛ_n_s_ɪ_t_ˌɪ_v k_ˈɒ_n_t_a_k_t d_ˌɜː_m_ɐ_t_ˈaɪ_t_ɪ_s]\
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A delayed hypersensitivity involving the reaction between sunlight or other radiant energy source and a chemical substance to which the individual has been previously exposed and sensitized. It manifests as a papulovesicular, eczematous, or exudative dermatitis occurring chiefly on the light-exposed areas of the skin.
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Word of the day
Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.