PAPILLAE TRUNCATAE

\pˈapɪlˌiː tɹˈʌnkɐtˌiː], \pˈapɪlˌiː tɹˈʌnkɐtˌiː], \p_ˈa_p_ɪ_l_ˌiː t_ɹ_ˈʌ_n_k_ɐ_t_ˌiː]\
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1846 - Medical lexicon: a dictionary of medical science
By Robley Dunglison

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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