ONCOGENE
\ˈɒnkə͡ʊd͡ʒˌiːn], \ˈɒnkəʊdʒˌiːn], \ˈɒ_n_k_əʊ_dʒ_ˌiː_n]\
Definitions of ONCOGENE
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By Princeton University
By DataStellar Co., Ltd
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Genes which can potentially induce neoplastic transformation. They include genes for growth factors, growth factor receptors, protein kinases, signal transducers, nuclear phosphoproteins, and transcription factors. When these genes are constitutively expressed after structural and/or regulatory changes, uncontrolled cell proliferation may result. Viral oncogenes have prefix "v-" before the gene symbol; cellular oncogenes (PROTO-ONCOGENES) have the prefix "c-" before the gene symbol.
By DataStellar Co., Ltd
Word of the day
Dopamine Acetyltransferase
- An enzyme that catalyzes the of groups from acetyl-CoA to arylamines. They have wide specificity for aromatic amines, particularly serotonin, and can also catalyze acetyl transfer between arylamines without CoA. EC 2.3.1.5.