MESUA FERREA

\mˈɛsjuːə fɛɹˈi͡ə], \mˈɛsjuːə fɛɹˈi‍ə], \m_ˈɛ_s_j_uː_ə f_ɛ_ɹ_ˈiə]\
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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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