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Mitogen-activated protein kinase kinase kinases (MAPKKKs) are serine-threonine protein kinases that initiate protein kinase signaling cascades. They phosphorylate MITOGEN-ACTIVATED PROTEIN KINASE KINASES; (MAPKKs) which in turn phosphorylate MITOGEN-ACTIVATED PROTEIN KINASES; (MAPKs).EC 2.7.10.-
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Pyramidal Cells
- Projection neurons in cerebral cortex hippocampus. Pyramidal cells a pyramid-shaped soma with apex apical dendrite pointed toward pial surface and other dendrites an axon emerging from base. The axons may have local collaterals but also project outside their cortical region.