LYMPHOCYTE ACTIVATING FACTOR
\lˈɪmfəsˌa͡ɪt ˈaktɪvˌe͡ɪtɪŋ fˈaktə], \lˈɪmfəsˌaɪt ˈaktɪvˌeɪtɪŋ fˈaktə], \l_ˈɪ_m_f_ə_s_ˌaɪ_t ˈa_k_t_ɪ_v_ˌeɪ_t_ɪ_ŋ f_ˈa_k_t_ə]\
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A soluble factor produced by monocytes, macrophages, and other cells which activates T-lymphocytes and potentiates their response to mitogens or antigens. IL-1 consists of two distinct forms, IL-1 alpha and IL-1 beta which perform the same functions but are distinct proteins. The biological effects of IL-1 include the ability to replace macrophage requirements for T-cell activation. The factor is distinct from INTERLEUKIN-2.
By DataStellar Co., Ltd
Word of the day
Dopamine Acetyltransferase
- An enzyme that catalyzes the of groups from acetyl-CoA to arylamines. They have wide specificity for aromatic amines, particularly serotonin, and can also catalyze acetyl transfer between arylamines without CoA. EC 2.3.1.5.