LEYDEN'S SPIRALS

\lˈe͡ɪdənz spˈa͡ɪ͡əɹə͡lz], \lˈe‍ɪdənz spˈa‍ɪ‍əɹə‍lz], \l_ˈeɪ_d_ə_n_z s_p_ˈaɪə_ɹ_əl_z]\

Definitions of LEYDEN'S SPIRALS

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1916 - Appleton's medical dictionary
By Smith Ely Jelliffe

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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