LEISHMAN-DONOVAN BODY
\lˈɛʃməndˈɒnəvˌan bˈɒdi], \lˈɛʃməndˈɒnəvˌan bˈɒdi], \l_ˈɛ_ʃ_m_ə_n_d_ˈɒ_n_ə_v_ˌa_n b_ˈɒ_d_i]\
Definitions of LEISHMAN-DONOVAN BODY
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.