INTUSSUSCEPT
\ɪntˈʌsəskˌɛpt], \ɪntˈʌsəskˌɛpt], \ɪ_n_t_ˈʌ_s_ə_s_k_ˌɛ_p_t]\
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.