IMMUNE COMPLEX DISEASE
\ɪmjˈuːn kˈɒmplɛks dɪzˈiːz], \ɪmjˈuːn kˈɒmplɛks dɪzˈiːz], \ɪ_m_j_ˈuː_n k_ˈɒ_m_p_l_ɛ_k_s d_ɪ_z_ˈiː_z]\
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Group of diseases mediated by the deposition of large soluble complexes of antigen and antibody with resultant damage to tissue. Besides SERUM SICKNESS and the ARTHUS REACTION, evidence supports a pathogenic role for immune complexes in many other systemic immunologic diseases including GLOMERULONEPHRITIS, systemic lupus erythematosus (LUPUS ERYTHEMATOSUS, SYSTEMIC) and POLYARTERITIS NODOSA.
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