HYPOCHROMATOSIS

\hˌa͡ɪpə͡ʊkɹˌə͡ʊmɐtˈə͡ʊsɪs], \hˌa‍ɪpə‍ʊkɹˌə‍ʊmɐtˈə‍ʊsɪs], \h_ˌaɪ_p_əʊ_k_ɹ_ˌəʊ_m_ɐ_t_ˈəʊ_s_ɪ_s]\

Definitions of HYPOCHROMATOSIS

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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