HOMEO BOX GENE
\hˈə͡ʊmiːˌə͡ʊ bˈɒks d͡ʒˈiːn], \hˈəʊmiːˌəʊ bˈɒks dʒˈiːn], \h_ˈəʊ_m_iː__ˌəʊ b_ˈɒ_k_s dʒ_ˈiː_n]\
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Highly conserved DNA sequences which have been identified in specific gene transcripts ranging from those of Drosophila melanogaster to mouse and human. Homeobox genes function, in part, to generate DNA-binding proteins with an evolutionary conserved approximately 60-residue sequence (HOMEODOMAIN PROTEINS).
By DataStellar Co., Ltd
Word of the day
Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.