HIV TAR ELEMENTS
\ˌe͡ɪt͡ʃˌa͡ɪvˈiː tˌiːˌe͡ɪˈɑːɹ ˈɛlɪmənts], \ˌeɪtʃˌaɪvˈiː tˌiːˌeɪˈɑːɹ ˈɛlɪmənts], \ˌeɪ_tʃ_ˌaɪ_v_ˈiː t_ˌiː__ˌeɪ_ˈɑː_ɹ ˈɛ_l_ɪ_m_ə_n_t_s]\
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Regulatory sequences important for viral replication that are located on each end of the HIV genome. The LTR includes the HIV ENHANCER, promoter, and other sequences. Specific regions in the LTR include the negative regulatory element (NRE), NF-kappa B binding sites , Sp1 binding sites, TATA BOX, and trans-acting responsive element (TAR). The binding of both cellular and viral proteins to these regions regulates HIV transcription.
By DataStellar Co., Ltd