GRAMICIDIN J
\ɡɹˈamɪsˌɪdɪn d͡ʒˈe͡ɪ], \ɡɹˈamɪsˌɪdɪn dʒˈeɪ], \ɡ_ɹ_ˈa_m_ɪ_s_ˌɪ_d_ɪ_n dʒ_ˈeɪ]\
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A group of antibiotics (ANTIBIOTICS, PEPTIDE) from Bacillus brevis. Gramicidin C or S is a cyclic, ten-amino acid polypeptide and gramicidins A, B, D are linear. Gramicidin is one of the two principal components of TYROTHRICIN which is used topically for gram-positive organisms. It is toxic to blood, liver, kidneys, meninges, and the olfactory apparatus.
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Word of the day
Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.