FRANCISCO DE RIOJA

\fɹansˈɪskə͡ʊ də ɹɪˈə͡ʊd͡ʒə], \fɹansˈɪskə‍ʊ də ɹɪˈə‍ʊd‍ʒə], \f_ɹ_a_n_s_ˈɪ_s_k_əʊ d_ə ɹ_ɪ__ˈəʊ_dʒ_ə]\
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1910 - Warner's dictionary of authors ancient and modern
By Charles Dudley Warner

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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