EUKARYOTIC TOPOISOMERASES II
\jˌuːkɐɹɪˈɒtɪk tˈɒpɔ͡ɪsˌə͡ʊmɹe͡ɪzɪz ɹˌə͡ʊmən tˈuː], \jˌuːkɐɹɪˈɒtɪk tˈɒpɔɪsˌəʊmɹeɪzɪz ɹˌəʊmən tˈuː], \j_ˌuː_k_ɐ_ɹ_ɪ__ˈɒ_t_ɪ_k t_ˈɒ_p_ɔɪ_s_ˌəʊ_m_ɹ_eɪ_z_ɪ_z ɹ_ˌəʊ_m_ə_n_ t_ˈuː]\
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Eukaryotic enzymes of the DNA TOPOISOMERASES, TYPE II class that catalyze ATP-dependent breakage of both strands of DNA, passage of the unbroken strands through the breaks, and rejoining of the broken strands. These enzymes bring about relaxation of the supercoiled DNA and resolution of a knotted circular DNA duplex. Isozymes of the eukaryotic DNA topoisomerase II consist of homodimers of alpha or beta subunits.
By DataStellar Co., Ltd
Word of the day
Snake's-head
- Guinea-hen flower; -- so called in England because its spotted petals resemble the scales of a snake's head.