ERBB GENES
\ˈɜːb bˈiː d͡ʒˈiːnz], \ˈɜːb bˈiː dʒˈiːnz], \ˈɜː_b b_ˈiː dʒ_ˈiː_n_z]\
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Retrovirus-associated DNA sequences (erbB) originally isolated from, or related to, the avian erythroblastosis virus (AEV). These genes code for the epidermal growth factor receptor (EGFR) family of receptors which is important in the control of normal cell proliferation and in the pathogenesis of human cancer. The genes include erbB-1 (GENES, ERBB-1), erbB-2 (GENES, ERBB-2), and erbB-3, all of which show abnormalities of expression in various human neoplasms.
By DataStellar Co., Ltd
