ENDOTHELIUM DERIVED NITRIC OXIDE
\ˌɛndə͡ʊθˈiːli͡əm dɪɹˈa͡ɪvd nˈa͡ɪtɹɪk ˈɒksa͡ɪd], \ˌɛndəʊθˈiːliəm dɪɹˈaɪvd nˈaɪtɹɪk ˈɒksaɪd], \ˌɛ_n_d_əʊ_θ_ˈiː_l_iə_m d_ɪ_ɹ_ˈaɪ_v_d n_ˈaɪ_t_ɹ_ɪ_k ˈɒ_k_s_aɪ_d]\
Sort: Oldest first
-
A free radical gas produced endogenously by a variety of mammalian cells. It is synthesized from arginine by a complex reaction, catalyzed by NITRIC OXIDE SYNTHASE. Nitric oxide is endothelium-derived relaxing factor. It is released by the vascular endothelium and mediates the relaxation induced by some vasodilators such as acetylcholine and bradykinin. It also inhibits platelet aggregation, induces disaggregation of aggregated platelets, and inhibits platelet adhesion to the vascular endothelium. Nitric oxide activates cytosolic guanylate cyclase and thus elevates intracellular levels of cyclic GMP.
By DataStellar Co., Ltd
Nearby Words
- endotheliomyxoma
- endotheliotoxin
- endothelium
- endothelium dependent relaxing factor
- endothelium derived growth factor synthase
- Endothelium Derived Nitric Oxide
- endothelium derived relaxant factor
- endothelium derived relaxing factor
- endothelium derived vasoconstrictor factor receptors
- endothelium derived vasoconstrictor factors
- endotheliums