E BOX SEQUENCES
\ˈiː bˈɒks sˈiːkwənsɪz], \ˈiː bˈɒks sˈiːkwənsɪz], \ˈiː b_ˈɒ_k_s s_ˈiː_k_w_ə_n_s_ɪ_z]\
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DNA locations with the consensus sequence CANNTG. ENHANCER ELEMENTS (GENETICS) may contain multiple copies of this element. E-boxes play a regulatory role in the control of transcription. They bind with basic helix-loop-helix (bHLH) type TRANSCRIPTION FACTORS. Binding specificity is determined by the specific bHLH heterodimer or homodimer combination and by the specific nucleotides at the 3rd and 4th position of the E-box sequence.
By DataStellar Co., Ltd
Word of the day
Dopamine Acetyltransferase
- An enzyme that catalyzes the of groups from acetyl-CoA to arylamines. They have wide specificity for aromatic amines, particularly serotonin, and can also catalyze acetyl transfer between arylamines without CoA. EC 2.3.1.5.