DOMINARUM AQUA

\dˈɒmɪnˌɑːɹəm ˈakwə], \dˈɒmɪnˌɑːɹəm ˈakwə], \d_ˈɒ_m_ɪ_n_ˌɑː_ɹ_ə_m ˈa_k_w_ə]\
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1846 - Medical lexicon: a dictionary of medical science
By Robley Dunglison

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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