COMPLEMENTARITY DETERMINING REGION 1
\kˌɒmplɪməntˈaɹɪti dɪtˈɜːmɪnɪŋ ɹˈiːd͡ʒən wˈɒn], \kˌɒmplɪməntˈaɹɪti dɪtˈɜːmɪnɪŋ ɹˈiːdʒən wˈɒn], \k_ˌɒ_m_p_l_ɪ_m_ə_n_t_ˈa_ɹ_ɪ_t_i d_ɪ_t_ˈɜː_m_ɪ_n_ɪ_ŋ ɹ_ˈiː_dʒ_ə_n w_ˈɒ_n]\
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Three regions (CDR1; CDR2 and CDR3) of amino acid sequence in the IMMUNOGLOBULIN VARIABLE REGION that are highly divergent. Together the CDRs from the light and heavy immunoglobulin chains form a surface that is complementary to the antigen. These regions are also present in other members of the immunoglobulin superfamily, for example, T-cell receptors (RECEPTORS, ANTIGEN, T-CELL).
By DataStellar Co., Ltd
Nearby Words
- complemental air
- complemental male
- complemental, complementary
- complementarity
- complementarity determining region
- Complementarity Determining Region 1
- complementarity determining region 2
- complementarity determining region 3
- complementarity determining region i
- complementarity determining region ii
- complementarity determining region iii