COLLAGENASE LIKE PEPTIDASE
\kˈɒle͡ɪd͡ʒnˌe͡ɪs lˈa͡ɪk pˈɛptɪdˌe͡ɪs], \kˈɒleɪdʒnˌeɪs lˈaɪk pˈɛptɪdˌeɪs], \k_ˈɒ_l_eɪ_dʒ_n_ˌeɪ_s l_ˈaɪ_k p_ˈɛ_p_t_ɪ_d_ˌeɪ_s]\
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A metalloproteinase which degrades helical regions of native collagen to small fragments. Preferred cleavage is -Gly in the sequence -Pro-Xaa-Gly-Pro-. Six forms (or 2 classes) have been isolated from Clostridium histolyticum that are immunologically cross-reactive but possess different sequences and different specificities. Other variants have been isolated from Bacillus cereus, Empedobacter collagenolyticum, Pseudomonas marinoglutinosa, and species of Vibrio and Streptomyces. EC 3.4.24.3.
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Word of the day
basidiomycota
- comprises fungi bearing the spores on basidium: Gasteromycetes (puffballs); Tiliomycetes (comprising orders Ustilaginales (smuts) and Uredinales (rusts)); Hymenomycetes (mushrooms; toadstools; agarics; bracket fungi); in some classification systems considered a division of kingdom comprises fungi bearing spores on a basidium; includes Gasteromycetes (puffballs) Tiliomycetes comprising the orders Ustilaginales (smuts) and Uredinales (rusts) Hymenomycetes (mushrooms, toadstools, agarics bracket fungi).