COAGULATION FACTOR XII
\kə͡ʊˌaɡjʊlˈe͡ɪʃən fˈaktə ɹˌə͡ʊmən twˈɛlv], \kəʊˌaɡjʊlˈeɪʃən fˈaktə ɹˌəʊmən twˈɛlv], \k_əʊ_ˌa_ɡ_j_ʊ_l_ˈeɪ_ʃ_ə_n f_ˈa_k_t_ə ɹ_ˌəʊ_m_ə_n_ t_w_ˈɛ_l_v]\
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Stable blood coagulation factor activated by contact with the subendothelial surface of an injured vessel. Along with prekallikrein, it serves as the contact factor that initiates the intrinsic pathway of blood coagulation. Kallikrein activates factor XII to XIIa. Deficiency of factor XII, also called the Hageman trait, leads to increased incidence of thromboembolic disease.
By DataStellar Co., Ltd
