CITRULLUS COLOCYNTHIS
\sˈɪtɹʌləs kˌə͡ʊləsˈɪnθɪz], \sˈɪtɹʌləs kˌəʊləsˈɪnθɪz], \s_ˈɪ_t_ɹ_ʌ_l_ə_s k_ˌəʊ_l_ə_s_ˈɪ_n_θ_ɪ_z]\
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.