CELL ADHESION MOLECULE RECEPTOR
\sˈɛl ɐdhˈiːʒən mˈɒlɪkjˌuːl ɹɪsˈɛptə], \sˈɛl ɐdhˈiːʒən mˈɒlɪkjˌuːl ɹɪsˈɛptə], \s_ˈɛ_l ɐ_d_h_ˈiː_ʒ_ə_n m_ˈɒ_l_ɪ_k_j_ˌuː_l ɹ_ɪ_s_ˈɛ_p_t_ə]\
Definitions of CELL ADHESION MOLECULE RECEPTOR
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A family of transmembrane glycoproteins consisting of noncovalent heterodimers. They interact with a wide variety of ligands including extracellular matrix glycoproteins, complement, and other cells, while their intracellular domains interact with the cytoskeleton. The integrins consist of at least three identified families: the cytoadhesin receptors, the leukocyte adhesion receptors, and the very-late-antigen receptors. Each family contains a common beta-subunit combined with one or more distinct alpha-subunits. These receptors participate in cell-matrix and cell-cell adhesion in many physiologically important processes, including embryological development, hemostasis, thrombosis, wound healing, immune and nonimmune defense mechanisms, and oncogenic transformation.
By DataStellar Co., Ltd
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- Wanting grace; unpleasing; disagreeable. Unkind, unfavourable.