BROXURIDINE
\bɹˈɒksjʊɹˌɪdiːn], \bɹˈɒksjʊɹˌɪdiːn], \b_ɹ_ˈɒ_k_s_j_ʊ_ɹ_ˌɪ_d_iː_n]\
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A nucleoside that substitutes for thymidine in DNA and thus acts as an antimetabolite. It causes breaks in chromosomes and has been proposed as an antiviral and antineoplastic agent. It has been given orphan drug status for use in the treatment of primary brain tumors.
By DataStellar Co., Ltd
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.