BLUMBERG'S SIGN
\blˈʌmbɜːɡz sˈa͡ɪn], \blˈʌmbɜːɡz sˈaɪn], \b_l_ˈʌ_m_b_ɜː_ɡ_z s_ˈaɪ_n]\
Definitions of BLUMBERG'S SIGN
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.