\blˈast tɹansfɔːmˈe͡ɪʃən], \blˈast tɹansfɔːmˈeɪʃən], \b_l_ˈa_s_t t_ɹ_a_n_s_f_ɔː_m_ˈeɪ_ʃ_ə_n]\
Definitions of BLAST TRANSFORMATION
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Morphologic alteration of small lymphocytes in culture into large blast-like cells able to synthesize DNA and RNA and to divide mitotically. It is induced by interleukins, mitogens such as phytohemagglutinins, and by specific antigens. It may also occur in vivo, as in graft rejection and chronic myelogenous leukemia.
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