\blˈast tɹansfɔːmˈe͡ɪʃənz], \blˈast tɹansfɔːmˈeɪʃənz], \b_l_ˈa_s_t t_ɹ_a_n_s_f_ɔː_m_ˈeɪ_ʃ_ə_n_z]\
Definitions of BLAST TRANSFORMATIONS
Sort: Oldest first
Morphologic alteration of small lymphocytes in culture into large blast-like cells able to synthesize DNA and RNA and to divide mitotically. It is induced by interleukins, mitogens such as phytohemagglutinins, and by specific antigens. It may also occur in vivo, as in graft rejection and chronic myelogenous leukemia.
By DataStellar Co., Ltd
Word of the day
- A relatively rare smooth muscle tumor found most frequently in the wall gastrointestinal tract, especially stomach. It similar to other tumors but may become very large and hemorrhage exhibit small cystic areas. Simple excision is almost always curative. (From Dorland, 27th ed; DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1354)