ARACHIDONATE 15 LIPOXYGENASE
\ɐɹˈakɪdə͡ʊnˌe͡ɪt fˈɪftiːn lˈɪpəksˌɪd͡ʒənˌe͡ɪs], \ɐɹˈakɪdəʊnˌeɪt fˈɪftiːn lˈɪpəksˌɪdʒənˌeɪs], \ɐ_ɹ_ˈa_k_ɪ_d_əʊ_n_ˌeɪ_t f_ˈɪ_f_t_iː_n l_ˈɪ_p_ə_k_s_ˌɪ_dʒ_ə_n_ˌeɪ_s]\
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An enzyme that catalyzes the oxidation of arachidonic acid to yield 15-hydroperoxyarachidonate (15-HPETE) which is rapidly converted to 15-hydroxy-5,8,11,13-eicosatetraenoate (15-HETE). The 15-hydroperoxides are preferentially formed in neutrophils and lymphocytes. EC 1.13.11.33.
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