ALKYLATIONS
\ˌalkɪlˈe͡ɪʃənz], \ˌalkɪlˈeɪʃənz], \ˌa_l_k_ɪ_l_ˈeɪ_ʃ_ə_n_z]\
Word of the day
Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.