T KININOGEN
\tˈiː kˈɪnɪnəd͡ʒən], \tˈiː kˈɪnɪnədʒən], \t_ˈiː k_ˈɪ_n_ɪ_n_ə_dʒ_ə_n]\
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Endogenous peptides present in most body fluids. Certain enzymes convert them to active KININS which are involved in inflammation, blood clotting, complement reactions, etc. Kininogens belong to the cystatin superfamily. They are cysteine proteinase inhibitors. HIGH-MOLECULAR-WEIGHT KININOGEN; (HMWK); is split by plasma kallikrein to produce BRADYKININ. LOW-MOLECULAR-WEIGHT KININOGEN; (LMWK); is split by tissue kallikrein to produce KALLIDIN.
By DataStellar Co., Ltd
Nearby Words
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- T Kininogen
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- t lymphocyte antigen receptor beta chain gene rearrangement
- t lymphocyte antigen receptor delta chain gene rearrangement