STRIATED MUSCLES

\stɹˈa͡ɪe͡ɪtɪd mˈʌsə͡lz], \stɹˈa‍ɪe‍ɪtɪd mˈʌsə‍lz], \s_t_ɹ_ˈaɪ_eɪ_t_ɪ_d m_ˈʌ_s_əl_z]\

Definitions of STRIATED MUSCLES

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2010 - Medical Dictionary Database
By DataStellar Co., Ltd

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ATP Binding Cassette, Sub Family B Proteins

  • A subfamily transmembrane the superfamily TRANSPORTERS that closely related in GLYCOPROTEIN. When overexpressed, function as dependent efflux pumps able extrude lipophilic drugs, especially ANTINEOPLASTIC AGENTS, from cells causing resistance (DRUG RESISTANCE, MULTIPLE). Although P-Glycoproteins share functional similarities to MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS they are two distinct subclasses of ATP-BINDING CASSETTE TRANSPORTERS, and have little sequence homology.
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