PHOSPHOPROTEIN PP60(V SRC)
\fˈɒsfəpɹˌə͡ʊtiːn pˌiːpˈiː sˈɪksti vˈiː ˌɛsˌɑːsˈiː], \fˈɒsfəpɹˌəʊtiːn pˌiːpˈiː sˈɪksti vˈiː ˌɛsˌɑːsˈiː], \f_ˈɒ_s_f_ə_p_ɹ_ˌəʊ_t_iː_n p_ˌiː_p_ˈiː s_ˈɪ_k_s_t_i__ v_ˈiː_ ˌɛ_s_ˌɑː_s_ˈiː]\
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A tyrosine-specific protein kinase encoded by the v-src oncogene of Rous sarcoma virus. The transforming activity of pp60 (v-src) depends on both the lack of a critical carboxy-terminal tyrosine phosphorylation site at position 527, and the attachment of pp60 (v-src) to the plasma membrane which is accomplished by myristylation of its N-terminal glycine. EC 2.7.11.-.
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Word of the day
Dopamine Acetyltransferase
- An enzyme that catalyzes the of groups from acetyl-CoA to arylamines. They have wide specificity for aromatic amines, particularly serotonin, and can also catalyze acetyl transfer between arylamines without CoA. EC 2.3.1.5.