OPSONIC INDEX
\ɒpsˈɒnɪk ˈɪndɛks], \ɒpsˈɒnɪk ˈɪndɛks], \ɒ_p_s_ˈɒ_n_ɪ_k ˈɪ_n_d_ɛ_k_s]\
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The power of leukocytes, under various conditions, to incorporate bacteria by phagocytosis as compared to the normal.
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The percentage of bacteria taken up by the leukocytes of diseased or immunized animals or men, as compared with the number taken up by the leukocytes of a healthy person. The opsonic power is now calculated by noting the dilution at which the serum still contains an opsonin, so that when mixed with bacteria and leukocytes, the latter will still show phagocytosis. This is called the dilution of opsonic extinction.
By Smith Ely Jelliffe
Word of the day
Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.