NMDA RECEPTOR IONOPHORE COMPLEX
\ˌɛnˌɛmdˌiːˈe͡ɪ ɹɪsˈɛptəɹ ˈa͡ɪənˌɒfɔː kˈɒmplɛks], \ˌɛnˌɛmdˌiːˈeɪ ɹɪsˈɛptəɹ ˈaɪənˌɒfɔː kˈɒmplɛks], \ˌɛ_n_ˌɛ_m_d_ˌiː__ˈeɪ ɹ_ɪ_s_ˈɛ_p_t_ə_ɹ ˈaɪ_ə_n_ˌɒ_f_ɔː k_ˈɒ_m_p_l_ɛ_k_s]\
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A class of ionotropic glutamate receptors characterized by affinity for N-methyl-D-aspartate. NMDA receptors have an allosteric binding site for glycine which must be occupied for the channel to open efficiently and a site within the channel itself to which magnesium ions bind in a voltage-dependent manner. The positive voltage dependence of channel conductance and the high permeability of the conducting channel to calcium ions (as well as to monovalent cations) are important in excitotoxicity and neuronal plasticity.
By DataStellar Co., Ltd
Nearby Words
- nls peptides
- nls receptor
- nlsbp
- nm
- nmda
- NMDA Receptor Ionophore Complex
- nmda receptors
- nmn adenylyltransferase
- nmr
- nmr imaging
- nmr spectroscopies