Definitions of M CSF

  1. A mononuclear phagocyte colony- stimulating factor ( M- CSF) synthesized by mesenchymal cells. The compound stimulates the survival, proliferation, and differentiation of hematopoietic cells of the monocyte- macrophage series. M- CSF is a disulfide- bonded glycoprotein dimer with a MW of 70 kDa. It binds to a specific high affinity receptor ( RECEPTOR, MACROPHAGE COLONY- STIMULATING FACTOR).