KALLOCRYL
\kˈaləkɹˌɪl], \kˈaləkɹˌɪl], \k_ˈa_l_ə_k_ɹ_ˌɪ_l]\
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.