HYPERMETRIAS
\hˌa͡ɪpəmˈɛtɹi͡əz], \hˌaɪpəmˈɛtɹiəz], \h_ˌaɪ_p_ə_m_ˈɛ_t_ɹ_iə_z]\
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Incoordination of voluntary movements that occur as a manifestation of CEREBELLAR DISEASES. Characteristic features include a tendency for limb movements to overshoot or undershoot a target (dysmetria), a tremor that occurs during attempted movements (intention TREMOR), impaired force and rhythm of rapidly alternating movements (adiadochokinesis), and GAIT ATAXIA. (From Adams et al., Principles of Neurology, 6th ed, p90)
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Word of the day
Dopamine Acetyltransferase
- An enzyme that catalyzes the of groups from acetyl-CoA to arylamines. They have wide specificity for aromatic amines, particularly serotonin, and can also catalyze acetyl transfer between arylamines without CoA. EC 2.3.1.5.