EPITOXOID
\ˈɛpɪtˌɒksɔ͡ɪd], \ˈɛpɪtˌɒksɔɪd], \ˈɛ_p_ɪ_t_ˌɒ_k_s_ɔɪ_d]\
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Syn.: toxon. A substance which has less affinity for an antitoxin than is possessed by the toxin. It is a primary secretory product of the diphtheria bacillus. It does not produce acute symptoms, but causes gradual emaciation and paresis in animals.
By Smith Ely Jelliffe
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.