ENDOTHELIAL GROWTH FACTOR
\ˌɛndə͡ʊθˈɛlɪəl ɡɹˈə͡ʊθ fˈaktə], \ˌɛndəʊθˈɛlɪəl ɡɹˈəʊθ fˈaktə], \ˌɛ_n_d_əʊ_θ_ˈɛ_l_ɪ__ə_l ɡ_ɹ_ˈəʊ_θ f_ˈa_k_t_ə]\
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These growth factors are soluble mitogens secreted by a variety of organs. The factors are a mixture of two single chain polypeptides which have affinity to heparin. Their molecular weight are organ and species dependent. They have mitogenic and chemotactic effects and can stimulate endothelial cells to grow and synthesize DNA. The factors are related to both the basic and acidic FIBROBLAST GROWTH FACTORS but have different amino acid sequences.
By DataStellar Co., Ltd
