CONTRACTILE ELEMENTS

\kəntɹˈakta͡ɪl ˈɛlɪmənts], \kəntɹˈakta‍ɪl ˈɛlɪmənts], \k_ə_n_t_ɹ_ˈa_k_t_aɪ_l ˈɛ_l_ɪ_m_ə_n_t_s]\

Definitions of CONTRACTILE ELEMENTS

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1916 - Appleton's medical dictionary
By Smith Ely Jelliffe

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ATP Binding Cassette, Sub Family B Proteins

  • A subfamily transmembrane the superfamily TRANSPORTERS that closely related in GLYCOPROTEIN. When overexpressed, function as dependent efflux pumps able extrude lipophilic drugs, especially ANTINEOPLASTIC AGENTS, from cells causing resistance (DRUG RESISTANCE, MULTIPLE). Although P-Glycoproteins share functional similarities to MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS they are two distinct subclasses of ATP-BINDING CASSETTE TRANSPORTERS, and have little sequence homology.
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