\kəntɹˈakta͡ɪl sˈɛl], \kəntɹˈakta‍ɪl sˈɛl], \k_ə_n_t_ɹ_ˈa_k_t_aɪ_l s_ˈɛ_l]\
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1920 - A dictionary of scientific terms.
By Henderson, I. F.; Henderson, W. D.
1916 - Appleton's medical dictionary
By Smith Ely Jelliffe

Word of the day

ATP Binding Cassette, Sub Family B Proteins

  • A subfamily transmembrane the superfamily TRANSPORTERS that closely related in GLYCOPROTEIN. When overexpressed, function as dependent efflux pumps able extrude lipophilic drugs, especially ANTINEOPLASTIC AGENTS, from cells causing resistance (DRUG RESISTANCE, MULTIPLE). Although P-Glycoproteins share functional similarities to MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS they are two distinct subclasses of ATP-BINDING CASSETTE TRANSPORTERS, and have little sequence homology.
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