CLELANDS REAGENT

\klˈɛləndz ɹɪˈe͡ɪd͡ʒənt], \klˈɛləndz ɹɪˈe‍ɪd‍ʒənt], \k_l_ˈɛ_l_ə_n_d_z ɹ_ɪ__ˈeɪ_dʒ_ə_n_t]\

Definitions of CLELANDS REAGENT

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2010 - Medical Dictionary Database
By DataStellar Co., Ltd

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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