CATABOLITE GENE ACTIVATOR PROTEINS
\kˈatˌabəlˌa͡ɪt d͡ʒˈiːn ˈaktɪvˌe͡ɪtə pɹˈə͡ʊtiːnz], \kˈatˌabəlˌaɪt dʒˈiːn ˈaktɪvˌeɪtə pɹˈəʊtiːnz], \k_ˈa_t_ˌa_b_ə_l_ˌaɪ_t dʒ_ˈiː_n ˈa_k_t_ɪ_v_ˌeɪ_t_ə p_ɹ_ˈəʊ_t_iː_n_z]\
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A transcriptional regulator in prokaryotes which, when activated by binding cyclic AMP, acts at several promoters. Cyclic AMP receptor protein was originally identified as a catabolite gene activator protein. It was subsequently shown to regulate several functions unrelated to catabolism, and to be both a negative and a positive regulator of transcription. Cell surface cyclic AMP receptors are not included (CYCLIC AMP RECEPTORS), nor are the eukaryotic cytoplasmic cyclic AMP receptor proteins, which are the regulatory subunits of CYCLIC AMP-DEPENDENT PROTEIN KINASES.
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