CARCINOID HEART DISEASES
\kˈɑːsɪnˌɔ͡ɪd hˈɑːt dɪzˈiːzɪz], \kˈɑːsɪnˌɔɪd hˈɑːt dɪzˈiːzɪz], \k_ˈɑː_s_ɪ_n_ˌɔɪ_d h_ˈɑː_t d_ɪ_z_ˈiː_z_ɪ_z]\
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Cardiac manifestation of MALIGNANT CARCINOID SYNDROME. It is a unique form of fibrosis involving the endocardium, primarily of the right heart. The fibrous deposits tend to cause constriction of the tricuspid and pulmonary valves. (DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1307)
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Word of the day
Dopamine Acetyltransferase
- An enzyme that catalyzes the of groups from acetyl-CoA to arylamines. They have wide specificity for aromatic amines, particularly serotonin, and can also catalyze acetyl transfer between arylamines without CoA. EC 2.3.1.5.